Abstract: Aiming at the difficulty of heat dissipation caused by high heat flux induced by high integration of the integrated host for radio detection-interference, a heat transfer network was constructed by analyzing the heat dissipation path of the host. Based on the theories of heat transfer and fluid mechanics, a mathematical model for thermal-fluid-solid coupled heat dissipation of the host was established. The ANSYS Icepak simulation platform was applied to create a three-dimensional full-scale numerical model for the host to study its heat dissipation mechanism. The results show that when the fan air volume is 56 m³/h, the integrated radio detection-interference host has good heat dissipation and low noise. When the heat sources of the power box are distributed on the same side, meanwhile the heat sources of the disturbance box and the navigation deception box are distributed on different sides, and the heat sources are close either to the air inlet or to the air outlet, the heat dissipation performance of the host is good with high efficiency. When the beam spacing of the bracket and device spacing are 15 mm and 10 mm respectively, the host has good heat dissipation performance and high structural strength with small mass and volume. When the height, thickness and spacing of the radiator fins are 7.5 mm, 1 mm and 5 mm, respectively, the heat dissipation is enhanced with light weight host.